Mannich-Type Reaction of N,O-Acetals with Ketones Mediated by a Combination of TiCl4 and PhSiCl3
スポンサーリンク
概要
- 論文の詳細を見る
A combination of TiCl4 and PhSiCl3 efficiently conducts the Mannich-type reaction of N,O-acetals with ketones to afford α-substituted cyclic amine derivatives in good yields. This method was applicable to preparation of azabicyclo compounds by the intramolecular Mannich-type reaction.
- The Japan Institute of Heterocyclic Chemistryの論文
- 2010-12-31
The Japan Institute of Heterocyclic Chemistry | 論文
- Catalytic Enantioselective Aziridination of Alkenes Using Chiral Dirhodium(II) Carboxylates
- Lewis Acid-Catalyzed Michael Addition Reactions of N-Boc-2-silyloxypyrroles to 3-Acryloyl-2-oxazolidinone
- Enantioselective Synthesis of 3-Arylindan-1-ones via Intramolecular C-H Insertion Reactions of α-Diazo-β-Ketoesters Catalyzed by Chiral Dirhodium(II) Carboxylates
- Dirhodium(II) Tetrakis[N-benzene-fused Phthaloyl-(S)-piperidinonate] as a Chiral Lewis Acid: Catalytic Enantioselective Aldol Reactions of Acetate-derived Silylketene Acetals and Aldehydes
- Direct and stereoselective synthesis of 2-azido-2-deoxy-β-D-mannosides using the phosphate method