[原著]Oral 5-Fluorouracil Therapy in Carcinoma of the Digestive Organs

概要

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Recently, attention has been increasingly focused on the oral administration of anticancer agents in the patients with cancer of the digestive organs ^<1,2,3,4,5,6)>. Especially, oral administration of 5-Fluorouracil (5-FU) seems to be useful as maintenance treatment because it showes anticancer activity with low toxicity^< 1,3,4,5,6)>. It is known that oral administration of 5-FU dry syrup in fasting patient, compared to intravenous injection of 5-FU, showes same mode of elevation of plasma 5-FU level^<7)>. Therefore, 5-FU dry syrup is useful, but 5-FU tablet which actsjust like 5-FU dry syrup is also desired because some patients with cancer think 5-FU dry syrup which they drink in syrup suspicious and become nervous. The authors report the experience of oral administration of 5-FU tablet in the patients with carcinoma of digestive organs.
琉球大学保健学部の論文