[原著]Anti-tumor Effects of The Fractions Derived From Some Cereals

概要

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A greate number of anti-tumor substances, being isolated from various sources including fungi, bacteria, yeasts, higher plants and herbs, have hitherto been reported^<3,4,6,7,12)>. They could be mainly classified as the polysaccharide or the lipo-polysaccharide group which is thought of as displaying alsmot the same carcinostatic effects on the transplanted tumors^<5,21,18)>. The carcinostatic mechanism of those agents has been taken to depend on their ability to act as a nonspecific stimulator to the immune systems to protect the host from growing tumors^<3,9,10,11)> In this study, four kinds of cereals which are rice, wheat, Job's tears and barnyard millet are dealt with as the source materials to find out the anti-tumor substances. Among the above-mentioned natural materials, a few have been used as ingredients of a native medicine. Especially, the grains of Job's tears have been regarded by the Eastern people as the materials having the special efficacy for a wart and used by them as a remedy. Also, it has been believed by some laity that the unpolished rice has the virtue for various consumptive diseases and malignant neoplasms. The experiments reported in this paper were undertaken to confirm the existence of anti-tumor substances in the grain or the cell-wall of those cereals through a subcutaneous application of the allogenic tumor, sarcoma-180 ascites tumor cells.
琉球大学保健学部の論文