[原著］粟国村におけるHBV感染の疫学

概要

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The examinations of sera for HBV markers and the liver function tests were carried out on 343 inhabitants (29% of the whole population) in Aguni Village, Okinawa. The RPHA technique was used for determination of HBsAg and the PHA for HBsAb. HBsAg was found in 3.8% of examinees and HBsAb in 37%. Further studies by usig the Enzyme immunoassay for HBeAg and HBeAb and the determination of subtype by Radioimmunoassay were performed on HBsAg positive sera. Two HBeAg positive cases and 10 HBeAb positive were found among them and all cases belonged to the subtype adw. Two cases with HBeAg showed abnormal results of the liver function tests such as elevated value of s-GOT (≧40KU/ml) and/or s-GPT (≧35KU/ml), while no abnormal findings in 10 cases with HBeAb. It was been noticed that there was a remarkable difference of the results of the liver function tests between the HBsAg positive bnd negative groups; the former showed abnormal value in 23% and latter only in 1.8%.
琉球大学医学部,Faculty of Medicine, University of the Ryukyusの論文