排泄性腎孟造影における非イオン性低浸透圧水溶性造影剤イオパミロン300の高齢者における使用経験

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1)平均年齢78歳(最低70歳,最高94歳)の高齢者について排泄性腎盂造影におけるiopamidol (Iopamiron 300)の造影効果と安全性を検討し,造影剤の尿中排泄率を測定した.2)造影効果についてウログラフィンと比較すると腎杯像がより鮮明であった.濃度計によるコントラスト値では有意差はなかった.イオパミロンのほうが明らかに良い例は19%で,81%は差はなかった.3)副作用は1例も認められなかった.4) Iopamiron 300 (300 mgI/ml) 100 ml静注後の尿中総排泄量は2Iopamidol (IOPAMIRON 300) was examined for excretory urography on 21 patients, between 70 and 94 years old, with reference to visualization, safety and urinary excretion. The results about visualization and safety were compared with those obtained with 60% Urografin. Iopamidol was demonstrated visualization nearly equivalent to that with Urografin, and 19% better pyelogram. Especially, calix showed a clearer contrast than those obtained with Urografin. None of the 21 old patients experienced any side effects or adverse reactions. No abnormalities were noted in serum chemistries. Iopamidol was not quickly excreted into the urine, only 19% during the first 2 hours, in elder patients.