尿中好酸球の臨床的意義

概要

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1)間質性膀胱炎における尿中好酸球は10例中9例に陽性で出現率は白血球数に比例した.好酸球の白血球に対する割合は約1/50かそれ以上であり,抗生剤の投与でも消失しなかった.2)急性膀胱炎でも29例中8例に陽性であった.好酸球の白血球数に対する割合は約1/50かそれ以下であり,抗生剤の投与で好酸球は白血球とともに消失した.3)尿中好酸球は組織中好酸球の浸潤程度を反映したThe clinical significance of eosinophils in urine was examined. Eosinophils were found in 9 out of 10 cases of interstitial cystitis, and there were more than 50 eosinophils in 50 fields in 6 of these cases. Although the number of eosinophils almost correlated with the number of leucocytes, the relationship between eosinophils and leucocytes in interstitial cystitis was different in acute and chronic cystitis. Since urinary eosinophils could be observed in cases of interstitial cystitis in which leucocytes were as low as 3 to 10 per field and the number of eosinophils was not decreased by chemotherapy, the urinary eosinophils in interstitial cystitis may be of allergic significance and reflect eosinophilic infiltration into the bladder wall.