早朝一過性血圧上昇を呈したプレクッシング症候群の2例

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49歳女,51歳女,クッシング症候群および2例の非機能性副腎腺腫の症例を加え,それらの血圧の日内変動を検討した結果,プレクッシング症候群はクッシング症候群にいたる過渡的疾患であり,暁星高血圧はその特徴的臨床症状と考えられたTwo adrenal tumors were incidentally discovered in the patients with dawn hypertension. They had no clinical features of Cushing's syndrome. These cases were regarded as pre-Cushing's syndrome by endocrinological evaluation. After adrenalectomy, the adrenal hormone regulation was normalized and dawn hypertension disappeared. Our findings suggest that dawn hypertension is a typical clinical sign of pre-Cushing's syndrome and this syndrome may represent a premature status of Cushing's syndrome.