女子尿道尖圭コンジローマの1例

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A case of female intraurethral condyloma acuminata is present in this report. A 52-year-old woman visited our hospital with the chief complaint of miction pain and bloody secretions. Thirty seven years previously, she had had a pudental tumor resected which was diagnosed as condyloma acuminata. Physical examination revealed two child-finger-head sized, polypoid tumors which arose from about 5 mm inside the external urethral orifice. Laboratory findings were negative for rapid plasma reagin card test (RPR), positive for treponema pallidum hemagglutination test (TPHA) and Trichomonas vaginalis in urine and vaginal secretion. Under the clinical diagnosis of condyloma acuminata, the tumors were resected. Histological examination revealed koilocytosis with mild dysplasia. The histochemical analysis of human papillomavirus (HPV) by in situ hybridization revealed positive for HPV type 31/33/51 and negative for HPV type 6/11 and 16/18. Histological examinations confirmed that the tumors were condyloma acuminata. No recurrence was seen at the 7th post-operative month.