ガンマナイフ治療が有効であった乳癌脳幹部転移の１例

概要

論文の詳細を見る
A 41-year-old woman was admitted to our hospital complaining of left hemiparesis, dysphonia, vertigo, and headache for 3 days. Six years earlier she had undergone standard radical mastectomy for left breast cancer. Three years earlier multiple lung metastases had been found, and the metastatic lesions were gradually increasing despite chemoendocrine therapy. Magnetic resonance imaging (MRI) scans showed a contrast-enhanced 1.5 cm-sized lesion in the right pons and 9 small contrast-enhanced lesions in the cerebrum. The pontine metastasis was the main lesion causing her symptoms. Gamma knife radiosurgery was performed on all these lesions,and treatment was also provided to prevent brain edema during and after gamma knife therapy. Her symptoms started to improve 6 days after the therapy, and she was discharged from our hospital after 14 days. Follow-up contrastenhanced MRI studies 1 month and 3 months after the therapy showed partial response in the pontine lesion and complete response in all cerebral lesions. However, the lung metastases were enlarged,and bone and soft tissue metastases were newly found. At present new chemoendocrine therapy is being performed for the generalized metastases. In this case, gamma knife radiosurgery was extremely useful for the brainstem metastasis from breast cancer.
信州医学会の論文