Regioselective Synthesis ofFluorohydrines via SN2-Type Ring-Opening of Epoxideswith TBABF-KHF2
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We found that the ring-opening fluorination of terminal epoxidesusing TBABF-KHF2 proceeds with high selectivity throughthe SN2 mechanism. As TBABF-KHF2 iseasily obtainable, is stable, and can be used in glassware, it canbe a useful reagent for 1-fluoro-2-alkanol synthesis from the terminalepoxides.
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関連論文
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- Regioselective Synthesis ofFluorohydrines via SN2-Type Ring-Opening of Epoxideswith TBABF-KHF2
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