Selective introduction of a fluorine atom into carbohydrates and a nucleoside by ring-opening fluorination reaction of epoxides
スポンサーリンク
概要
- 論文の詳細を見る
Ring-opening fluorination reactions of epoxides using tetrabutylammonium bifluoride(TBABF)-KHF2, or Et3N-3HF under microwave irradiation were applied for theintroduction of a fluorine atom into the carbohydrate molecules. When TBABF-KHF2was used as the fluorination reagent, a fluorine atom was introduced regioselectivelyand various functional groups can tolerate the conditions. When Et3N-3HF was usedunder microwave irradiation, the reaction time could be remarkably shortened comparedwith the conventional oil-bath heating.
- Elsevierの論文
著者
関連論文
- Selective introduction of a fluorine atom into carbohydrates and a nucleoside by ring-opening fluorination reaction of epoxides
- Regioselective Synthesis ofFluorohydrines via SN2-Type Ring-Opening of Epoxideswith TBABF-KHF2
- A Practical Synthetic Method for Iodoarene Difluorides without Fluorine Gas and Mercury Salts
- Selective trifluorination of alkyl aryl sulfides using IF5
- Fluorination of Sulfides Using IF_5-Et_3N-3HF
- Fluorocyclization of Unsaturated Aldehydes to Five - or Six-membered Cyclic Fluoroalcohols
- Selective Electrochemical Formyl Hydrogen-Exchange Fluorination of Aliphatic Aldehydes to Prepare Acyl Fluorides Using HF-Base Solutions
- Boron Trifluoride Etherate Mediated 1,4-Addition of (1-Alkynyl)diisopropoxyboranes to α,β-Unsaturated Ketones. A Convenient New Route to 3-Alkynyl Ketone Synthesis