Radiation-induced Tumors -Study Based on Biopsied and Surgical Materials-

概要

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So-called radiation-induced tumor cases following radiation therapy have been collected for the purpose of elucidation the relationship between ionizing radiation and carcinogenesis. Presented in this paper is a summary of cases obtained from biopsied and surgical materials. Materials were 64,082 cases with tumor or tumor-like lesion registered to the Nagasaki Tumor Tissue Registry during a 12-year period from 1973 to 1984. The criteria used for determination of radiation-induced tumor were 1) the past history of radiation therapy, 2) the evidence of tumor developing at the site of irradiation and 3) the latent period of five years or more. As a result, 6 male cases and 26 female cases, totalling 32 cases, of radiation-induced tumor were detected. These 32 cases were compiled after being classified into four categories of 1) malignant tumor developing after radiation therapy for malignant tumor, 2) malignant tumor after radiation therapy for benign condition, 3) benign tumor after radiation therapy for malignant tumor, and 4) benign tumor after radiation therapy for benign condition.