Relationship between C－MYC Expression and the Cell Cycle in HL－6０ Cells －Flow Cytometric Analysis－
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概要
- 論文の詳細を見る
By flow cytometric measurement of cellular DNA, c-myc protein and cell volume, we attempted to assess the relationship between c-myc gene expression and the cell cycle in exponentially growing human promyrlocytic leukemia cell line (HL-60). The protein product of c-myc gene was stained by an indirect immunofluorescence method using a specific antiserum to human c-myc protein. Bivariate distributions of cellular DNA, the c-myc protein contents and cell volume demonstrated the direct evidence that the c-myc protein increases with the progression of the cell cycle and then is halved by cell division.
- Yamaguchi University Graduate School of Medicineの論文
著者
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Takahashi Manabu
Second Department Of Pathology Yamaguchi University School Of Medicine
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Orita Tetsuji
Department Of Neurosurgery Yamaguchi University School Of Medicine:department Of Neurosurgery Shuto
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Murakami Tomoyuki
Second Department Of Pathology Yamaguchi University School Of Medicine
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Sasaki Kohsuke
山口大学 病理
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