The Relationship of Blood Pressure with Intra- Or extracellular and Bone Calcium Merabolisms in the Elderly
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We investigated the correlations of blood pressure with intra- or extracellular and bone calcium matabolisms in the elderly. We measured serum calcium (Ca), inorganic phosphorus (Pi), C-terminal parathyroid hormone fragment (PTH-C), and calcitonin. Intracellular free calcium ([Ca2+]I) in platelet and erythrocyte was measured by fura- 2/AM from dual excitation wavelength using a fluorescence spectrophotometer. We calculated bone mineral content (BMC) of lumbar vertebral body using a calibration phantom by computed tomography. Systolic blood pressure had significant positive correlation with platelet [Ca2+]I (r=0.691 ; p<0.01), but had no significant correlations with any of these parameters. Serum Ca, Pi, [Ca2+]I of platelet and erythrocyte had no significant correlations with PTH-C, calcitonin and BMC. BMC had a significant negative correlation with age (r=-0.684; p<0.01), but had no correlations with the other examination parameters. These results suggest that systolic blood pressure in the elderly may be affected by calcium metabolism.
- Yamaguchi University Graduate School of Medicineの論文
Yamaguchi University Graduate School of Medicine | 論文
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