Troglitazone-Induced Liver Injury Diagnosed by a Laparoscopic Examination in Its Asymptomatic Stage
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概要
- 論文の詳細を見る
A 56-year-old diabetic woman had been taking glibenclamide (10 mg daily) plus voglibose (0.6 mg daily) for recent 4 years without a successful response. Three months after troglitazone (400 mg daily) was started in addition to glibenclamide, liver dysfunction was found by chance. She demonstrated no symptoms, histological examination, however, revealed a substantial hepatocelluar necrosis mainly in the peri-central vein areas, which was consistent with an idiosyncratic drug reaction. Since troglitazoneinduced liver dtsfunction was strongly suggested, administaration of troglitazone was terminated and abnormal values of liver-chemistry returned to normal in two months.
- Yamaguchi University Graduate School of Medicineの論文
著者
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Yamada Toshiki
First Department Of Internal Medicine Gifu University Graduate School Of Medicine
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Yamada Toshiki
Department Of Hematology/oncology The Institute Of Medical Science University Of Tokyo
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Yoshikawa T
First Department Of Internal Medicine Gifu University Graduate School Of Medicine
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YAMADA Tetsuya
Division of Hematology, Department of Medicine, Yamaguchi Prefecture Central Hospital
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Takeda Koumei
Division Of Hematology Department Of Medicine Yamaguchi Prefecture Central Hospital
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Yamada Tetsuya
First Department Of Internal Medicine Gifu University Graduate School Of Medicine
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Yamada T
Inst. Space And Astronautical Sci. Kanagawa Jpn
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Yamada Tetsuya
The Third Department Of Internal Medicine Yamaguchi University School Of Medicine
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Inoue Yasushi
Department Of Internal Medicine Yamaguchi Prefecture General Hospital
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Katsuki Kensaku
Division Of Hematology Department Of Medicine Yamaguchi Prefecture Central Hospital
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Kamei Toshiaki
Yamaguchi Prefectural Medical Center Yamaguchi Jpn
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