反鼻の薬理学的研究(第1報) : 反鼻の寒冷ストレスおよび振盪ストレス負荷マウスに対する作用

概要

論文の詳細を見る
A water extract (HW) from Agkistrodon Japonicae "Hampi," an animal crude drug prepared from Agkistrodon blomhoffi blomhoffi BOIE, was investigated for its effect on mice exposed to cold stress (4℃) or to oscillation movement stress. When administered orally, HW was found to protect cold stress-exposed mice from the decrease in motor activity, the lowering of rectal temperature and the increase in serum GOT activity. Repeated administration of HW was found to be slightly effective in preventing the reduction of spontaneous and exploratory movements of mice exposed to oscillation movement stress, when tested by hole cross and climbing tests. These results suggested that HW was effective in protecting mice from fatigue induced by exposure to stress.
日本生薬学会の論文
1985-12-20