マルチスケール・マルチフィジックス心臓シミュレータUT-Heart(プレナリー・スピーカー)

概要

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Our heart simulator, UT-Heart, is based on the fluid-structure interaction finite element method consisting of both solid and fluid elements which correspond to the heart tissue and blood, respectively. In each tissue element the molecular model of cardiac excitation-contraction coupling is implemented and cell models are electrically connected. The excitation initiated at the sino-atrial node propagates to the entire heart with the aid of conduction system, and blood is ejected into aorta which is connected to systemic circulation analogue. In addition the cardiac cells are modeled by finite elements to achieve the goal of seamless integration. For this multiscale simulation, which is inevitably nonlinear, an efficient homogenization algorithm utilizing massively parallel computation was developed. Putting emphasis on the multiscale simulation, the outline of UT-Heart is introduced.
一般社団法人日本機械学会の論文
2011-09-25