Application of Secondary Ionization Mass Spectrometry-Linked Scanning Analysis to an Identification Test for Ginseng in Chinese Herbal Preparations

概要

論文の詳細を見る
Secondary ionization mass spectrometry (SIMS)-linked scanning analysis was conducted to detect ginseng in Chinese herbal preparations. Methanol extracts of Chinese herbal preparations were centrifuged and then passed through filter paper before being used as the test sample. Ginseng in the sample was detected by using ginsenoside Rb_1 (Rb_1) as an indicator. Measurement was carried out by the linked scanning system at constant B/E with Xenon gas to produce primary ions, glycerol as a matrix and potassium chloride as a metal substrate. In the SIMS-linked scanning spectra of Chinese herbal preparations containing ginseng (Juzentaiho-to, Kami-kihi-to and Saikan-to), a quasi-molecular ion ([M+K]^+) and its daughter ion peaks were observed at m/z 1147 and m/z 985, 805, 737 and 381, respectively, indicating the structure of Rb_1. The SIMS-linked scanning method was found to be adequate for detecting ginseng in Chinese herbal preparations, because it is more simple and rapid and gives more accurate and reliable result than conventional methods.
日本生薬学会の論文
1992-12-20