243 HA/β-TCP複合材料の力学的特性に及ぼす擬似体液浸漬の影響(生体・環境適合型材料の創製と特性評価(3),ものづくりにおける基礎研究と先端技術の融合)

概要

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Bioactive ceramics attracts attentions as materials of the bone implant, because their high biocompatibility. For example, hydroxyapatite (HA) has bone-bonding ability, and β-ricalcium phosphate (β-TCP) has a high bioresorbability. In this study, HA/P-TCP composites with different content of β-TCP (5,10,20wt%) were prepared by wet mixing of HA and β-TCP powder, compaction of the powders and sintering. Bending strength of HA/β-TCP composites were measured before and after soaking in the simulated body fluid (SBF) up to 4weeks. The bioactivity of HA/β-TCP composites was also evaluated by soaking in SBF up to 4weeks. It was found that the relative density decreased as content percentage of β-TCP increased. It was also found that the bending strength decreased rapidly after 1 week soaking, whereas it doesn't decrease from 2weeks to 4weeks soaking. This result suggested that the apatite layer formed on the surface in SBF reinforced the specimen in spite of the dissolution of the surface constituents.
一般社団法人日本機械学会の論文
2010-11-27