J0203-1-4 医療用無痛穿刺採血投薬ユニットの開発に関する研究([J0203-1]ドラッグデリバリーシステム:技術開発と医療応用(1))

概要

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This research purpose is to develop minimal medical units applying heated actuations of the Shape Memory Alloy (SMA) transducers using the medical Ti-Ni, in order to enable minimal hypodermic invasive microvolume blood suction or drug delivery by equipping nontoxic and minimal edged microneedle to be created in our laboratory. We focused on lymphocytes for immunotoxin and erythrocytes for glucose level in blood. In the last year paper, we had already reported that the joule heating of the earlier SMA multi-transducer unit might be useful for indenting blood vessels because they whose outer diameter was larger than that of the needle lay in 2 mm deep from surface skin. Therefore, this paper reported the improved mechanisms of the unit and its actuations by low DC inputs. As for the actuation of multi-face foil transducer for blood suction, when applying DC 1.5 V and 2 A, the foil transducer recovered as plane state as before multi-face forming in room temperature. The foil transducer started actuation 4.4 s later from start of heating, recovered plane state 8.3 s later more.
2010-09-04