2A1-M09 再生医療用cell processingロボットの研究開発

概要

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We've been working for developing of scaffold free cell delivery system, and show good regeneration of rabbit osteochondral defect until more than two years by implantation of molded mesenchymal stem cells construct without use of exogenous factors. The entire procedure is simple, yet, it takes time and labor to build a single construct even experienced hands. There is a possibility that a large amount of constructs will be demanded in clinical, manual procedure may have difficulty in maintain quality of the constructs, raise risk of contamination, or raise costs of human operator. In this study, we developed a cell processing robot for building Scaffold free HD MACs(High-density mesenchymal stem cell autologus constructs). And evaluated the efficacy of the entire systems. In result, we are able to build the Scaffold free HD MACs as same as manual procedure without contamination.
一般社団法人日本機械学会の論文
2009-05-25