進行肺癌および転移性肺腫瘍に対する体外循環下全身温熱療法の成績

概要

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Whole body hyperthermia (WBH) has been employed for the treatment of lung cancer and metastatic lung tumor in our hospital since 1981. All of our patients passed away in the period following WBH and a survival period of 50% was found in our study. WBH was carried out in primary 34 cases with Stage IIIB or Stage IV advanced cancer. The patients had an average of 54.7 years of age. In the primary cancer gruop, there were a total of 24 males and 10 females. In addition, there were 18 cases of metstatic lung tumor, consisting of 10 males and 8 females. The latter group showed an average of 50.1 years of age. In the primary lung cancer group, 50% survival periods were found with the average duration being 12.0 months in non-small lung cancer and 3.0 months in small lung cancer. PR or MR was noted in 17.6% of the primary cancer group. In the metastatic lung tumor group, a 50% survival period was found with the average duration of time being 3.0 months for males while that of females was 11.0 months. From our study we have found that WBH therapy was not effective in decreasing tumor size, but was very useful in reducing pain. Survival periods were found to have been longer in old patients, in non-small cell cancer patients and in relatively active patients.
東京女子医科大学の論文
2000-12-25