糖尿病網膜症の診断と治療(<シリーズ>「糖尿病の治療」(11))

概要

論文の詳細を見る
Diabetic retinopathy has been the worldwide leading cause of blindness in working age adults. It is characterized by gradually progressive alteration in the retinal microvasculature, leading to retinal nonperfusion, increased vasopermeability, and pathologic intraocular proliferation of retinal vessels. Severe vision loss from diabetes is primarily a result of intraocular angiogenesis and moderate visual loss principally occurs from leakage of retinal vessels. The risk of severe vision loss from proliferative diabetic retinopathy is approximately 40% in 6 years after its onset, if not treated with laser panretinal photocoagulation. The risk of moderate visual loss from diabetic macular edema is approximately 33% in 3 years after its onset. Appropriate and timely laser photocoagulation can reduce the risk of severe visual loss by more than 95%. Similarly, the risk of moderate visual loss from diabetic macular edema can be reduced by 50% with appropriate focal laser photocoagulation. With experienced ophthalmic evaluation, diabetic retinopathy can be detected in it early stages. Existing therapies are remarkably effective when administered at an appropriate time during the disease process. In addition, improvement of systemic glycemic control is associated with a delay in the onset or a slowing of the progression of diabetic retinopathy.
東京女子医科大学の論文