HISTOCHEMICAL STUDIES ON THE SURFACE OF THE TROPHOBLAST : PART 2. EFFECTS OF NEURAMINIDASE ON THE IMPLANTATION SITES OF MICE

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概要

• 論文の詳細を見る

• Effects administering neuraminidase and concomitant treatment with the hormone upon implantation sites of pregnant mice have been studied histochemically. In addition, effects of neuraminidase and hormone on fetoplacental development and growth have been examined. Administration of neuraminidase on pregnant mice around the time when ova begin implanting reduced both the proportion of mice with ovum implants and the number of implants per pregnant mouse. Microscopically the presence of a large haemorrhagic area at the attachment of the decidua and the trophoblast was observed. According to histochemical findings, the Prussian blue reaction was not present on the surface of the embryo and the trophoblast. When progesterone or hCG was given to mice similarly treated with neuraminidase the suppressive effect of neuraminidase was not weakened sufficiently. These results suggest that neuraminidase influences the sialomucin of the cell surface of the trophoblast and surface mucins may protect fetal trophoblast from immunological destruction.

• 名古屋市立大学の論文
• 1977-08-28

著者

• 鈴森 謙次

  Department Of Obstetrics And Gynecology Nagoya City University Medical School

関連論文

• HISTOCHEMICAL STUDIES ON THE SURFACE OF THE TROPHOBLAST : PART 2. EFFECTS OF NEURAMINIDASE ON THE IMPLANTATION SITES OF MICE
• HISTOCHEMICAL STUDIES ON THE SURFACE OF THE TROPHOBLAST : PART 1. HISTOCHEMICAL STUDIES ON THE SURFACE OF NORMAL AND SPONTANEOUSLY ABORTED HUMAN TROPHOBLAST

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