難消化性デキストリン配合混合茶飲料の食後中性脂肪上昇抑制効果および長期摂取、過剰摂取における安全性の検討

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We developed a mixing tea beverage containing resistant maltodextrin. In the present study, we investigated whether the beverage would suppress the postprandial elevation of serum triglyceride levels. A double-blinded crossover study was performed to assess the effects of the test beverage intake on postprandial serum triglyceride levels. Subjects were 50 healthy adults (serum triglyceride 100-250mg/dL). Subjects had test beverages with resistant maltodextrin or without resistant maltodextrin (placebo) with fat-rich meal (fat 40g). Blood samples were taken before and 1, 2, 3, 4, 6 hours after the food ingestion and serum triglyceride levels were measured. Intake of resistant maltodextrin beverage group significantly suppressed the level of serum triglyceride observed at 1, 2, 3, 6 hours after food ingestion as compared with that of the placebo (p<0.05). Also, a randomized double-blind, placebo-controlled study was performed to assess the safety of excessive intake or long term intake of the beverage (20 subjects for long term intake, 40 subjects for excessive intake). In the long term intake trial or excessive intake trial, the subjects were divided into two groups; drinking beverage with resistant maltodextrin group or drinking beverage without resistant maltodextrin group. Subjects were given regular amount of beverage (resistant maltodextrin: 5g) a day for 12 weeks (long term intake trial), three times as much as regular amount of beverage a day for weeks (excessive intake trial). As a result, there were no clinical problems in the blood examinations and physical examinations on both trials. No adverse reactions were observed. These results suggested that intake of the resistant maltodextrin supplemented beverage suppresses postprandial serum triglyceride levels without any safety problem.
2009-04-28

難消化性デキストリン配合混合茶飲料の食後中性脂肪上昇抑制効果および長期摂取、過剰摂取における安全性の検討

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