血清Caeruloplasmin,血清銅と,精神疾患,向精神薬ならびに実験的肝障害との関連について

概要

論文の詳細を見る
About 29 schizophrenic patients, 10 epileptics, 4 depressions, 8 other patients, 5 normal healthy persons, 56 total, the levels of serum Caeruloplasmin and copper was determined, and inquired these levels into a changes of some drugs and conditions of patients, adding, to the experimental liver damage. The results were as follows ; 1). Between schizophrenic patients and normal healthy persons, these levels of serum Caeruloplasmin were reveald some remarkable changes. 2). About schizophrenic patients, these finding were especially remarkable in the cases with active hallucination or delusion, and these levels are related to these cases. 3). Between schizophrenic patients and normal healthy persons, there was hard to reveal quickly about serum copper levels. 4). As p-phenylenediaminc oxidations rate was inhibited by ascorbic acid, it may easily imazine, the levels of ascorbic acid will be decreased in schizophrenic patients. 5). Although the changes of these levels lying in such medication of Neuroleptics caurse, was not determind, which these changes was tend to somewhat decrease as compared with the control levels. 6). It will be abbe to thinking that these levels are elevated by sex hormon. 7). Under the conditions of experimental liver damage, these levels are remarkably elevated, and the elevations of these levels are related to the degenerations rate of liver tissue studging with the microscopic method.
千葉大学の論文
1962-11-28