ヨーグルトの作用に関する実験的研究 : 第2編 腸管伝染病原菌感染防止作用に就て

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概要

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• In part I of the present paper, the author reported the results of his experiments on the changes in the numbers of intestinal bacteria, an increase in weight and the nature of fecal discharges of 4 groups of mice which were fed on the basal diet alone, yoghurt, whole milk and skim milk in addition to the basal diet. Part IC deals with the results of experiments on Yoghurt's action of inhibiting the growth of pathogenic organisms in the intestines. The rat typhoid bacterium, S 9 Salmonella tyhimurium(1406), (M.L.D. 1×10^<-5>mg), was orally given to three groups of young, male mice fed on the basal diet alone, and yoghurt and skim milk in addition to the basal diet. Then, the presence or absence of the symptoms of the disease, general condition, the nature of feces and the changes in the numbers of intestinal bacteria of the three groups of mice were examined in chronological sequence. The typhoid bacteria had been incubated in slant agar mediums for 24 hours at 37℃; 8 mg of them had been weighed by a platinum loop and dissolved in about 0.5-1.0 cc of bouillon. A piece of bread imbued with them was given to a mouce. In the same way or in the previous experiments, the number of typhoid bacteria excreted in the feces was computed in E.M.B. culture mediums every other day. The numbers of intestinal bacteria found in the feces were computed prior to, 7 days after and 13 days after the rat typhoid bacteria had been given. Examination of the general condition, the nature of feces, the number of the typhoid bacteria excreted in the feces, the time elapsed before the feces have become free of the rat typhoid bacteria, and the number of deaths in three groups of mice has led the author to the findings summarized as follows :. 1) The group fed on yoghurt in addition to the basal diet has shown the strongest resistance to an infection with the rat typhoid bacteria. 2) There has been no significant difference between hydrogen ion concentrations of the three groups of mice. This would suggest that, as has been claimed, there is some other function in yoghurt besides the acid production by L. bulgaric. 3)it would seem that the administration of yoghurt, is effective to a certain degree in inhibiting the growth of pathogenic organisms in the intestines. (S 9 Salmonella typhimurium has been supplied by the National Institute of Preventive Hygiene.)

• 千葉大学の論文
• 1957-01-28

著者

• 安藤 良夫

  千葉大学医学部衛生学教室

関連論文

• 17. ガス攪拌による消化効果について(第422回千葉医学会例会 衛生学公衆衛生学教室連合会)
• ヨーグルトの作用に関する実験的研究 : 第1編 動物成長に及ぼす影響に就て
• ヨーグルトの作用に関する実験的研究 : 第2編 腸管伝染病原菌感染防止作用に就て
• 7. ヨーグルトの動物成長に及ぼす影響について(I.一般演説,谷川教授開講十周年記念,第329回千葉医学例会,衛生学教室例会連合会演説要旨)

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