小人症の臨床的研究

概要

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Studies were made of 20 children with no symptoms and signs of any disease expcept being "of small stature". The following results were obtained: 1. Children in whom stature is smaller than the average stature of the children of same age, same sex and same race by over 2.58 times the standard deviation (σ) have been defined as dwarfs, and those who do not fall under this category (1.32〜2.57σ) have tentatively been termed semi-dwarfs. Of 20 children studied, 11 were dwarfs and 9 semi-dwafs, according to this method of classification. 2. This definition has been proved to be acceptable both theoretically and practically; the clinical picture, endocrine functions (as manifested in urine gonadotropin and 17 KS levels and thyroid uptake of I^<131>) and the course of development during the period of no treatment, as well as the case reports published elsewhere, served to support the author's view. 3. The 1.1 dwarfs consisted of 3 primordial dwarfs, 1 pituitary dwarf with tumor and 7 idiopathic pituitary dwarfs. 4. Treatment was given to 6 dwarfs, with 5 of ( them showing a slight improvement.