第1篇 疫痢,赤痢患児の腸内菌叢の研究
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概要
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(1) The author performed investigations on the numbers of various microorganisms isolated from the feces of infants and children suffering from ekiri and dysentery. In ekiri the numbers of conform bacteria and Clostridium germs (mainly Cl. welchii) were larger, those of the bacteria of the genus Shigella were also slightly larger, and those of enterococcus germs tended to be smaller, thanin dysentery. In dysentery the numbers of the bacteria of the genus Shigella were predominant, and those of normal intestinal bacteria were uniformly small. The above findings have led the author to presume that, in ekiri, the infection with the bacteria of the genus Shigella would be followed by the existence of an abnormal condition of puetrefaction in the intestines, while, in dysentery, the bacteria of the genus Shigella wonld prevail upon, and inhibit the growth of, normal intestinal bacteria. (2) The bacteria collected after washing the feces, and those isolated from the feces, of ekiri patients were capable of producing amines, while those collected after washing the feces of dysentry patients were not. This will prove that the intestinal bacteria in ekiri provide favorable condition for the production of amines. (3) Histamine and tyramine were detected in the feces and urine in ekiri, but they were non-existent in dysentery. This will show that, in ekiri, amines are produced in the intestines, absorbed in the blood and excreted in the urine. This will also illustrate that a function of the liver to . counteract poisons has been diminished. It would seem, therefore, that combined actions of various amines produced as a result of an abnormal condition of the puetrefaction existing in the intestines following the infection with the bacteria of the genus Shigella might be partly responsible for the syndrome of poisoning characteristic of ekiri.
- 千葉大学の論文
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- 第2篇 疫痢,赤痢患児の腸内菌叢に及ぼす抗生物質投与の影響
- 第1篇 疫痢,赤痢患児の腸内菌叢の研究