A Case of Persistent Mullerian Duct Syndrome with Sertoli Cell Tumor and Hydrometra in a dog(Internal Medicine)

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概要

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• A 10-year-old Miniature Schnauzer with bilateral cryptorchidism and male external genitalia was referred with a history of abdominal enlargement. Upon exploratory laparotomy, two tumors and a connecting structure similar to fluid-filled uterus were recognized. After cytological and bacterial examinations of the fluid and histological examination, this dog was diagnosed with bilateral Sertoli cell tumor with hydrometra. The karyotype of this dog was 78, XY and the sry gene was detected positive by PCR. We diagnosed this dog as a case of persistent Mullerian duct syndrome (PMDS), which is male pseudohermaphroditism. This is the first report regarding the incidence of PMDS in Miniature Schnauzers in Japan, and it suggests the involvement of a gene carrier.

• 2009-03-25

著者

• 神田 鉄平

  鳥取大学農学部獣医学科獣医内科学研究室

• KANDA Teppei

  Department of Veterinary Medicine, Faculty of Agriculture, Tottori University

• Kanda Teppei

  Department Of Veterinary Internal Medicine Faculty Of Agriculture Tottori University

• Matsuu Aya

  Department Of Veterinary Internal Medicine Faculty Of Agriculture Tottori University

• Okamoto Yoshiharu

  Veterinary Neurology And Oncology Faculty Of Agriculture Tottori University

• Nagano Masashi

  Theriogenology Faculty Of Agriculture Tottori University

• HASHIZUME Takuya

  Department of Veterinary Internal Medicine, Faculty of Agriculture, Tottori University

• SUGIYAMA Akihiko

  Laboratory Medicine, Faculty of Agriculture, Tottori University

• Hashizume Takuya

  Department Of Veterinary Internal Medicine Faculty Of Agriculture Tottori University

• Sugiyama Akihiko

  Laboratory Medicine Faculty Of Agriculture Tottori University

• 神田 鉄平

  食敷芸術科学大学生命科学部

• 神田 鉄平

  倉敷芸術科学大学 生命科学部 生命動物科学科

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