Aortic Pulse Wave Velocity Predicts Cardiovascular Mortality in Middle-Aged and Elderly Japanese Men(Vascular Medicine)
スポンサーリンク
概要
- 論文の詳細を見る
Background: Aortic pulse wave velocity (PWV) is widely used as a noninvasive index of arterial stiffness and was used in the present study to investigate the relationship between PWV and cardiovascular mortality in the middle-aged and elderly Japanese population using a longitudinal study design. Methods and Results: From 1988 to 2003, a total of 3,960 men (50-69 years old at baseline) who underwent medical check-ups and measurement of PWV, which was standardized for diastolic blood pressure, were recruited and divided into 4 groups according to the PWV values. The average follow-up period was 8.2 years. Mortality from all-causes and from cardiovascular disease significantly increased as PWV increased in the entire follow-up period. Multivariate-adjusted relative risks of all-cause and cardiovascular disease mortality for the highest quartile of PWV (>9.0m/s) were 1.28 (95% confidence interval (CI) 0.97-1.68) and 1.83 (95%CI 1.02-3.29), respectively, compared with the lowest quartile (<7.5m/s). Conclusions: An increased PWV can predict cardiovascular mortality in middle-aged and elderly Japanese men.
- 社団法人日本循環器学会の論文
- 2009-02-20
著者
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YAMAMOTO Hideya
Department of Cardiovascular Medicine, Graduate School of Biomedical Sciences, Hiroshima University
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Shokawa Tomoki
Department of Molecular and Internal Medicine, graduate School of Biomedical Sciences, Hiroshima Uni
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Yamamoto Hideya
Department Of Cardiovascular Medicine Graduate School Of Biomedical Sciences Hiroshima University
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Yamamoto Hideya
Department Of Molecular And Internal Medicine Graduate School Of Biomedical Sciences Hiroshima Unive
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Inoue Noriko
Hiroshima City Medical Association Clinical Laboratory Center
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Maeda Ryo
Hiroshima City Medical Association Clinical Laboratory Center
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Kawakami Hideshi
Research Institute for Radiation Biology and Medicine
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Ito Chikako
Grand Tower Medical Court Life Care Clinic
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Sasaki Hideo
Hiroshima Atomic-Bomb Casualty Council Health Management and Promotion Center
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Shokawa Tomoki
Department Of Cardiovascular Medicine Hiroshima University
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Shokawa Tomoki
Department Of Molecular And Internal Medicine Graduate School Of Biomedical Sciences Hiroshima Unive
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Sasaki Hideo
Hiroshima A-bomb Casualty Council Health Management And Promotion Center
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Inoue Noriko
Hiroshima A-bomb Casualty Council Health Management & Promotion Center
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