Metabolic Syndrome Predicts 10-Year Mortality in Non-Diabetic Patients Following Coronary Artery Bypass Surgery
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概要
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Background Metabolic syndrome (MetS) is a risk factor for cardiovascular disease and mortality, but, the relationship between MetS and survival after coronary artery bypass grafting (CABG) remains unclear. Methods and Results The outcomes of patients with and without MetS were analyzed. Patients who had undergone CABG at Juntendo University Hospital between January 1984 and December 1992 were enrolled. The survival search was performed by the end of 2000. The patients were categorized by the existence of preoperative MetS using the modified American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) definition with body mass index instead of waist circumference. MetS was present in 551 (46.6%) patients and absent in 632 (53.4%). Preoperative MetS was associated with long-term poor prognosis in terms of all-cause death (hazard ratio (HR) 1.34; 95%confidence interval (CI) 1.03-1.74; p=0.028) and cardiac death (HR 2.31; 95%CI 1.36-3.92; p=0.002) in non-diabetic patients. These differences in the mortality of the 2 groups were more obvious after 10 years. However, among the patients with diabetes, the presence of MetS was not related to long-term mortality. Conclusions Preoperative MetS predicted increased all-cause and cardiac mortality, especially after 10 years, in non-diabetic patients undergoing CABG.
- 社団法人日本循環器学会の論文
- 2008-08-20
著者
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DAIDA Hiroyuki
Department of Cardiology, Juntendo University School of Medicine
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Naito Hisashi
Sports Clinic Juntendo University Hospital
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Kobayashi Takashi
Department Of Cardiology Kobe City Medical Center General Hospital
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Miyauchi Katsumi
Department of Cardiovascular Medicine, Juntendo University, School of Medicine
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HIROSE Hitoshi
Department of Cariovascular Surgery, Shin-Tokyo Hospital
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Takazawa Kenji
Department of Cardiology, Tokyo Medical University Hachioji Medical Center
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Takazawa Kenji
Department Of Cardiology And Medicine Jichi Medical School
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Takazawa Kenji
Department Of Cardiovascular Surgery Social Insurance Chuo General Hospital
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Matsuyama Koshi
Clinical Education Center Kumamoto University Hospital
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Hirose Hitoshi
Department Of Cardiovascular Surgery Juntendo University School Of Medicine
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Hirose Hitoshi
Department Of Cardiothoracic Surgery Drexel University College Of Medicine
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KASAI Takatoshi
Department of Cardiology, Juntendo University, School of Medicine
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Miyauchi Katsumi
Department Of Cardiovascular Medicine Juntendo University
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Miyauchi Katsumi
Department Of Cardiology Juntendo University School Of Medicine
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Kajimoto Kan
Department of Cardiovascularsurgery, Juntendo University
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Hosoda Yasuyuki
Department of Cardiovascularsurgery, Juntendo University
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Amano Atsushi
Department of Cardiovascular Surgery, Juntendo University, School of Medicine
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Yamamoto Taira
Department of Crdiovascular Surgery, Juntendo University
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Yanagisawa Naotake
Department of Cardiology, Juntendo University School of Medicine
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Niinami Hiroshi
Department of Cardiovascular Surgery, Juntendo University School of Medicine
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HOSODA Yasuyuki
胸部外科
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Hosoda Yasuyuki
Department Of Cardiovascular Surgery Kawasaki Saiwai Hospital
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Yamamoto Taira
Department Of Cardiovascular Surgery Juntendo University School Of Medicine
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Yamamoto Taira
順天堂大学 胸部外科
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Yamamoto Taira
順天堂大学 医学部心臓血管外科学
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Kurata Takeshi
Department Of Cardiology Juntendo University School Of Medicine
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Kasai Takatoshi
Department Of Cardiology Juntendo University
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Hosoda Yasuyuki
Department Of Cardiothoracic Surgery Juntendo University School Of Medicine
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Hosoda Yasuyuki
Department Of Cardiovascularsurgery Juntendo University
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Miyauchi Katsumi
Department Of Cardiovascular Medicine Juntendo University School Of Medicine
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Amano Atsushi
Department Of Cardiovascular Surgery Juntendo University School Of Medicine
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Kajimoto Kan
Department Of Cardiology Juntendo University School Of Medicine
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Hosoda Yasuyuki
Jyuntendou University
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Daida Hiroyuki
Department Of Cardiology
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Kawasumi Masahiko
Department Of Cardiology Juntendo University School Of Medicine
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Kajimoto Kan
Department Of Cardiovascular Surgery Juntendo University
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Niinami Hiroshi
Department Of Cadiovascular Surgery Tokyo Women's Medical University Medical Center East
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Yamamoto Taira
Department Of Cardiovascular Center Toranomon Hospital
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Kajimoto Kan
Department Of Cardiovascular Surgery Juntendo University School Of Medicine
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Hosoda Yasuyuki
Department Of Thoracic And Cardiovascular Surgery Juntendo University
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Yanagisawa Naotake
Department Of Cardiology Juntendo University School Of Medicine
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Yanagisawa Naotake
Department Of Cardiology Juntendo University
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Yamamoto Taira
Department Of Cardiovascular Surgery Juntendo University
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Hosoda Yasuyuki
The Department Of Thoracic And Cardiovascular Surgery Juntendo University
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Amano Atsushi
Department Of Cardiothoracic Surgery Juntendo University School Of Medicine
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Niinami Hiroshi
Department Of Cardiovascular Surgery Juntendo University School Of Medicine
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Kita Toru
Division Of Translational Research Kyoto Medical Center National Hospital Organization
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Yamamoto Taira
Department of Cardiothoracic Surgery, Juntendo University, School of Medicine
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