自己制御型発熱素子の腫瘍(マウスB16メラノーマ)抑制効果(生体磁気・医療応用)

概要

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Hyperthermia is a method of treating cancer that uses heat to destroy tumors. Soft heating has been proposed as one method of treating hyperthermia. This is where the thermosensitive ferrite inserted into the tumor as a heating element produces heat in a high-frequency magnetic field. We applied soft heating in this study. Heat element developed can control temperature automatically, referring the Curie-point of the thermosensitive ferrite. The heat element consists of a thermosensitive ferrite and metal ring coated on it. The purpose of the metal ring wrapped to ferrite is to increase heat quantity compared with that of ferrite alone. The effect of the heat element in murine B-16 Melanoma model is examined. As a result, the tumors of mice were locally heated to the point at which tumor is necrotized.
社団法人日本磁気学会の論文
2008-05-01