10 カミヤツデおよびツキヌキサイコより得られるOleanane系Triterpene配糖体の構造と2,3の反応

概要

論文の詳細を見る
Summary of new oleanane triterpenoid glycosides from the leaves of Tetrapanax papyriferum and Bupleurum rotundifolium L. are presented. The reaction of oleanane triterpenoid glycosides (1),(6) and (7)with reagent A gave 11-oxo compounds (5) and (8). This fact indicated that this reagent was useful for the oxidation of an allyl alcohol and an allyl ether. On the other hand, the reaction of oleanane triterpenoids (14),(15),(16) and (17) with reagent A gave 16-oxo derivertives (12),(18),(19) and (20), while compounds (21) and (24) with this reagent gave 21-oxo derivertives (26) and (27). Reagent A is also very useful to the selective oxidation of 16- and 21-axial hydroxyl group. Preparation of Reagent A A mixture of CrO_3, pyridine and n-BuOH saturated with water were kept at room temperature for 1 day. The mixture was concentrated under reduced pressure and the residue was washed with water and CHCl_3, and dried under reduced pressure.
天然有機化合物討論会の論文
1979-09-20