肺臓フォスファティード加牛血清に依る實驗的心筋炎に關する研究(第4報)

概要

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The conclusions are as follows: 1) Clinically; body weight, temperature, blood pressure, blood picture, roentgenogram and etc. showed no remarkable changes. Protein, urobilinogen and urobilin reactions in urine were temporarily or continuously positive after the reinjection. Ecg. indicated myocardial damage. Serologically; PPR. before and after the reinjection were positive. 2) Histologically; on the one hand in the heart the diffus interstitial myocarditis and KLINGE's perivascular granuloma were seen, on the ohter hand in the lung slight changes. 3) In this experiment I could not produce the soecific allergic changes in the lung tissue successfully. The fact that I found more intense allergic changes in the heart than in the lung will suggest that the rabbit-lung-phosphatide consists of a component which has an intense affinity to the heart. Therefore I think that I must try to remove this component from the rabbit-lung-phosphatide in the future.
社団法人日本循環器学会の論文
1954-11-20