結核菌に依る心筋炎並びに菌血症に關する實驗的研究(第3報) : 第1編家兎心筋フォスファティード加結核菌に依る實驗的心筋炎(3)

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Histological View In this experiment I found intensely diffus basophilic cell irfiltration and muscle fiber degeneration in myocardium compared with those of the control. The most remarkable change in myocardium was perivascular granuloma, so called rheumatoid or tuberculoid, which consisted of basophilic cell infiltration, including plasma cell, and being accompanied with fibrous scar. Therein I could not find typical tubercles, of course such as LANGHAN's giant cells and caseous lesions. In the lung tissue were found epitheloid cell nodules and desquamative pneumonia, and in the testicles many typical tubercles and caseous lesions, but these changes made no essential differences compared with the control. In the other organs, such as liver, spleen, kidney and etc. were found a few tuberculous nodules without giant cells and caseous lesions but these changes were very slight compared with myocardial lesions.
社団法人日本循環器学会の論文
1954-10-20