ニコチンによる實驗的心筋炎の研究 : 第3報ニコチン加牛血清に於る實驗的心筋炎(3)

概要

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With the mixture of nicotine and oxen sera allergic myocarditis was found not only electrocardiographically, but also histologically in the rabbits' hearts. As control experiments show, any kinds of inflammations, of course any other pathologic changes, were never called into being in the rabbits' hearts which were treated with nicotine alone. So we must attach importance to the fact that only the mixture of nicotine and oxen sera produces myocarditis just as the mixture of digitalis and oxen sera did in Noda's reports. The matter, that nicotine a kind of substances which have aphinity to the heart muscle such as digitalis, precipitates the allergic inflammatory changes especially in the myocardium and these changes are selectively broken out as were seen in my previous reports, corraborates Prof. Maekawa's theory about the organ specifity of allergic changes and throws a fresh light on the study of allergy.
社団法人日本循環器学会の論文
1951-01-20