Clinical Study of the Acute Effects of Intravenous Nifekalant on the Defibrillation Threshold in Patients With Persistent and Paroxysmal Atrial Fibrillation
スポンサーリンク
概要
- 論文の詳細を見る
Background Antiarrhythmic agents are considered to have significant effects on the defibrillation energy requirement, so this study investigated the effects of nifekalant on defibrillation. Methods and Results Forty-two patients with persistent atrial fibrillation (AF) underwent electrical cardioversion via intracardiac electrode catheters prior to and after the intravenous administration of nifekalant. The success rate of the defibrillation and change in the defibrillation threshold using sequential incremental defibrillation energy deliveries was investigated. In addition, the parameters that could predict the beneficial effects of nifekalant were also assessed. Nifekalant significantly decreased the defibrillation energy requirement in 13 of the 42 cases, and nifekalant also converted AF to sinus rhythm with an identical energy to that of the last unsuccessful defibrillation in 21 of 42 cases. The success of defibrillation seemed to be dependent on significant prolongation of the intracardiac atrial electrogram intervals during AF by the nifekalant. Conclusions Intravenous nifekalant significantly improved the electrical defibrillation efficacy in patients with persistent AF that was resistant to defibrillation, without any serious adverse effects.
- 社団法人日本循環器学会の論文
- 2007-12-20
著者
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Okishige Kaoru
Heart Center, Yokohama-City Minato Red Cross Hospital
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AZEGAMI Koji
Heart Center
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Miyagi Naoto
Yokohama City Minato Red Cross Hospital Heart Center
-
Miyagi Naoto
Heart Center Yokohama City Bay Red Cross Hospital
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Okishige Kaoru
Yokohama City Minato Red Cross Hospital
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Okishige Kaoru
Cardiac Electrophysiology Laboratory Cardiovascular Department Yokohama Red Cross Hospital
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Asami Kohichi
Department Of Cardiovascular Medecine Tokyo Medical And Dental University
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Azegami Kouji
Department Of Cardiovascular Disease Yokohama Red Cross Hospital
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Hiezima Kazumasa
1st Dept. Of Internal Medicine Tokyo Medical And Dental University
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Hiejima Kazumasa
Department Of Allied Health Sciences Tokyo Medical And Dental University School Of Medicine
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Asami Kohichi
Heart Center Yokohama City Bay Red Cross Hospital
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Okishige Kaoru
Cardiovascular Division Yokohama Red Cross Hospital
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Azegami Kouji
Heart Center, Yokohama-city Bay Red Cross Hospital
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Hirao Kenzo
Cardiovascular Division, Tokyo Medical & Dental University
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Uehara Hiroki
Heart Center, Yokohama-city Bay Red Cross Hospital
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Nakamura Kentarou
Heart Center, Yokohama-city Bay Red Cross Hospital
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Wakimoto Hirofumi
Heart Center, Yokohama-city Bay Red Cross Hospital
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Ohba Kageyuki
Heart Center, Yokohama-city Bay Red Cross Hospital
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Shimabukuro Mitsuo
The Second Department of Medicine, Ryukyu University
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Isobe Mistuaki
Cardiovascular Division, Tokyo Medical and Dental University
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Oba Kageyuki
Yokohama City Minato Red Cross Hospital
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Wakimoto Hirofumi
Yokohama City Minato Red Cross Hospital
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Wakimoto Hirofumi
Heart Center Yokohama City Bay Red Cross Hospital
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Wakimoto Hirofumi
Cardiovascular Division St Marianna University School Of Medicine
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Nakamura Kentarou
Second Department Of Internal Medicine University Of The Ryukyus
-
Azegami Koji
Department Of Cardiology Yokohama City Minato Red Cross Hospital
-
Ohba Kageyuki
Heart Center Yokohama City Bay Red Cross Hospital
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Uehara Hiroki
Heart Center Yokohama City Bay Red Cross Hospital
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Hiejima Kazumasa
The First Department Of Internal Medicine Tokyo Medical And Dental University School Of Medicine
-
Okishige Kaoru
Department Of Cardiology Yokohama City Minato Red Cross Hospital
-
Iemitsu Motoyuki
Graduate School Of Medicine Tokyo Medical And Dental University
-
Shimabukuro Mitsuo
The Second Department Of Medicine Ryukyu University
-
Hirao Kenzo
1st Dept. Of Internal Medicine Tokyo Medical And Dental University
-
Hirao Kenzo
Division Of Cardiology Heart Institute Chiba-nishi General Hospital
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Okishige Kaoru
Heart Center
-
Miyagi Naoto
Heart Center Yokohama-city Bay Red Cross Hospital
-
Okishige Kaoru
The Cardiac Electrophysiology Laboratory Yokohama Red Cross General Hospital
-
Shimabukuro Michio
The Second Department Of Medicine Ryukyu University
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Nakamura Kentarou
The Second Department Of Internal Medicine Ryukyu University
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Ohnishi Kentaro
Department Of Cardiovascular Medicine Musashino Red Cross Hospital
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Nakamura Kentaro
Second Department Of Internal Medicine University Of The Ryukyus
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Azegami Kouji
Heart Center Yokohama City Bay Red Cross Hospital
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Azegami Kouji
Yokohama City Minato Red Cross Hospital
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Hiejima K
The First Department Of Internal Medicine Tokyo Medical And Dental University School Of Medicine
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