A New Labdane Diterpene from the Flowers of Solidago canadensis
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概要
- 論文の詳細を見る
A new labdane diterpene, 9α,16ζ-dihydroxy-6-oxo-7,13-labdadien-15,16-olide (solicanolide, 1) and six known compounds identified as quercetin (2), 3-O-caffeoylquinic acid (3, neochlorogenic acid), 5-O-caffeoylquinic acid (4, chlorogenic acid), 4,5-di-O-caffeoylquinic acid (5), 3,5-di-O-caffeoylquinic acid (6) and 3,4-di-O-caffeoylquinic acid (7) were isolated from the flowers of Solidago canadensis. To our knowledge, compound 7 was isolated for the first time in S. canadensis. This work describes the isolation of compounds 1-7 and the structure elucidation of a new compound identified as compound 1. Solicanolide (1) showed cytotoxic activity against A549 (IC_<50>: 13±2μM), DLD-1 (IC_<50>: 26±2μM) and WS1 (IC_<50>: 17±1μM) cell lines.
- 公益社団法人日本薬学会の論文
- 2008-01-01
著者
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Bradette-hebert Marie-eve
Laseve Departement Des Sciences Fondamentales Universite Du Quebec A Chicoutimi
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LEGAULT Jean
LASEVE, Departement des Sciences Fondamentales, Universite du Quebec a Chicoutimi
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LAVOIE Serge
LASEVE, Departement des Sciences Fondamentales, Universite du Quebec a Chicoutimi
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PICHETTE Andre
LASEVE, Departement des Sciences Fondamentales, Universite du Quebec a Chicoutimi
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Pichette Andre
Laseve Departement Des Sciences Fondamentales Universite Du Quebec A Chicoutimi
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Legault Jean
Laseve Departement Des Sciences Fondamentales Universite Du Quebec A Chicoutimi
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Lavoie Serge
Laseve Departement Des Sciences Fondamentales Universite Du Quebec A Chicoutimi
関連論文
- A New Labdane Diterpene from the Flowers of Solidago canadensis
- New Labdane Diterpenes from the Stem Bark of Larix laricina