New Labdane Diterpenes from the Stem Bark of Larix laricina
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概要
- 論文の詳細を見る
Two new labdane diterpenes, cis-19-hydroxyabienol (1) and 8α-hydroxy-12Z,14-labdadien-19-al (2), along with another labdane described for the first time in the genus Larix, 19-acetoxy-13S-hydroxy-8(17),14-labdadiene (3) and a stilbene, 3-methoxy-3,3',5'-trihydroxystilbene (4), were isolated from the stem bark of Larch (Larix laricina). Their structures were established by standard chemical and spectroscopic methods. Compounds 2 and 3 were shown to be moderately cytotoxic against A-549, DLD-1 and normal skin flbroblast cell lines, WS1. Compound 1 was found to be selectively active against colon carcinoma cell lines, DLD-1.
- 公益社団法人日本薬学会の論文
- 2006-10-01
著者
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Mshvildadze Vakhtang
Laseve Departement Des Sciences Fondamentales Universite Du Quebec A Chicoutimi
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Morin Pierre
Laseve Departement Des Sciences Fondamentales Universite Du Quebec A Chicoutimi
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LEGAULT Jean
LASEVE, Departement des Sciences Fondamentales, Universite du Quebec a Chicoutimi
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LAVOIE Serge
LASEVE, Departement des Sciences Fondamentales, Universite du Quebec a Chicoutimi
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PICHETTE Andre
LASEVE, Departement des Sciences Fondamentales, Universite du Quebec a Chicoutimi
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LEBRUN Maxime
LASEVE, Departement des Sciences Fondamentales, Universite du Quebec a Chicoutimi
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Lebrun Maxime
Laseve Departement Des Sciences Fondamentales Universite Du Quebec A Chicoutimi
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Pichette Andre
Laseve Departement Des Sciences Fondamentales Universite Du Quebec A Chicoutimi
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Legault Jean
Laseve Departement Des Sciences Fondamentales Universite Du Quebec A Chicoutimi
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Lavoie Serge
Laseve Departement Des Sciences Fondamentales Universite Du Quebec A Chicoutimi
関連論文
- A New Labdane Diterpene from the Flowers of Solidago canadensis
- New Labdane Diterpenes from the Stem Bark of Larix laricina