Histopathological Study on the Distribution of Langerhans Cells in Oral Mucosa
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概要
- 論文の詳細を見る
Background & Aims: Some oral mucosal diseases display clear predispositions toward certain sites ofoccurrence. Oral lichen planus is one such disease, and is thought to have some relationships with cell-mediated immunity leading to a tendency to develop on the buccal mucosa. The aim of this study wasto investigate the distribution of Langerhans cells in various sites of oral mucosa. Methods: Immunohistochemicalexamination using an anti-S100 antibody was performed for 47 samples of healthy oralmucosa and skin. Results: S100-positive cells were more frequent in lining mucosa than in masticatorymucosa. Significantly more S100-positive cells were found in buccal mucosa than in other sites.Conclusions: Langerhans cells are positive for S100 and are thought to represent antigen-presentingcells. These cells were most frequent in buccal mucosa, a result that is in accordance with the predispositionof oral lichen planus.
- 北関東医学会の論文
- 2007-11-01
著者
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Yamaguchi Toru
Department of Ethnology and Archaeology, Keio University
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NEGISHI Akihide
Department of Stomatology and Maxillofacial Surgery, Gunma University Graduate School of Medicine
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MOGI Kenji
Departments of Oral and Maxillofacial Surgery Gunma University, Faculty of Medicine
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Yamaguchi Toru
Department Of Ethnology And Archaeology Keio University
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Mogi Kenji
Department Of Stomatology And Maxillofacial Surgery Gunma University Graduate School Of Medicine
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Mogi Kenji
Department Of Stomatology And Maxillofacial Surgery Subdivision Of Oncology Division Of Biosystem Me
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Negishi Akihide
Department Of Stomatology And Maxillofacial Surgery Subdivision Of Oncology Division Of Biosystem Me
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Negishi Akihide
Department Of Oral And Maxillofacial Surgery School Of Medicine Gunma University
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Mogi Kenji
Department Of Cardiovascular Surgery Funabashi Municipal Medical Center
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Yamaguchi Toru
Department Of Stomatology And Maxillofacial Surgery Subdivision Of Oncology Division Of Biosystem Medicine Course Of Medical Science Gunma University Graduate School Of Medicine
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Yamaguchi Toru
Department of Electronic System Engineering, Tokyo Metropolitan Institute of Technology
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