主幹脳動脈硬化病変でのApolipoprotein(a)の局在 : 抗Apoprotein(a)抗体とplasminogenの交差性の基礎的検討を含めて

概要

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High blood Lipoprotein (a) (Lp(a)) is a risk factor of independent cerebral infarction. Primary structure of Apo (a) is similar with plasminogen, and a kringlel-3 part of plasminogen suffers a loss, and a kringle4 repetition part is inserted. In addition, mass of Apo (a) is prescribed by the repetition number of kringle4. There are arteriosclerosis and a lot of epidemiologic studies of Lp (a), but there is little localized examination by an arteriosclerosis mental change caused by a disease by immunohistochemical technique. Furthermore, there is not the report that I make views to deny the antiApo (a) antibody and immunity intersection characteristics of plasminogen in an immunohistochemical study by an antiApo (a) antibody clear, and showed a cerebral blood vessel. I performed fundamental examination about immunohistochemical examination by an antiApo (a) antibody and immunity intersection characteristics with plasminogen of an antiApo (a) antibody this time. As a result, there is not the antiApo (a) antibody which I used so as to be able to ignore immunity intersection characteristics with plasminogen, and it seems that I can evaluate local existence of Lp (a) in each tissue only by an tissue absorption examination in future.
東京文化短期大学の論文
2007-03-12