Use of Colloidal Particles to Improve the Biocatalytic Activity of Microorganisms(Microbiology & Fermentation Industry)

概要

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Two cell-associated yeast enzyme systems have been shown to be influenced by the addition of biochemically inert colloidal particles to the growth medium. Titers of the alcohol oxidase enzyme system of Pichia pastoris and the β-glucosidase system of Candida wickerhamii were amplified up to 3-fold through the addition of small (5-10 g/l) amounts of commercial aluminum oxide particles. This discovery is of importance from an applied perspective as a means of increasing biocatalytic efficiency. As well, it provides a means of studying the physiological changes associated with cell sorption, independent of confounding influences such as diffusional limitations that are normally associated with film growth.
社団法人日本農芸化学会の論文
1990-07-23