Synthesis and Antibacterial Activity of Bis[2-amino-4-phenyl-5-thiazolyl] Disulfides

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概要

• 論文の詳細を見る

• Different dimeric disulfides, having the basic skeleton of bis[2-amino-4-phenyl-5-thiazolyl] disulfides were synthesized in a straightforward manner from acetophenones. 2-Amino-4-phenyl-1,3-thiazoles were prepared by the reaction of thiourea with substituted acetophenones in the presence of iodine which were then converted to the title compounds. All the compounds were subjected to preliminary evaluation for their biological activity against Gram positive and Gram negative bacteria. Some of the assayed compounds showed marked activity against Bacillus cereus and Pseudomonas aeruginosa.

• 2007-07-01

著者

• Siddiqui Hamid

  Institute of Chemistry, University of the Punjab

• ZIA-UR-REHMAN Muhammad

  Applied Chemistry Research Center, PCSIR Laboratories Complex

• Siddiqui Hamid

  Institute Of Chemistry University Of The Punjab

• AHMADA Naveed

  Institute of Chemistry, University of the Punjab

• WEAVER George

  Chemistry Department, Loughborough University

• LUCAS Paul

  Chemistry Department, Loughborough University

• Lucas Paul

  Chemistry Department Loughborough University

• Ahmada Naveed

  Institute Of Chemistry University Of The Punjab

• Weaver George

  Chemistry Department Loughborough University

• Zia-ur-rehman Muhammad

  Applied Chemistry Research Center Pcsir Laboratories Complex

• Zia-ur-rehman Muhammad

  Applied Chemistry Res. Center Pcsir Laboratories Complex

• Ahmad Naveed

  Institute of Chemistry, University of the Punjab

関連論文

• Antimicrobial and Antileishmanial Studies of Novel (2E)-3-(2-Chloro-6-methyl/methoxyquinolin-3-yl)-1-(Aryl)prop-2-en-1-ones
• Synthesis and Antibacterial Activity of Bis[2-amino-4-phenyl-5-thiazolyl] Disulfides
• Synthesis of Potential Biologically Active 1,2-Benzothiazin-3-yl-quinazolin-4(3H)-ones
• Synthesis, Characterization and Hypoglycemic Activity of Zn(II), Cd(II) and Hg(II) Complexes with Glibenclamide
• Synthesis, Spectroscopic and Cytotoxic Studies of Biologically Active New Schiff Bases Derived from p-Nitrobenzaldehyde

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