Classification and Determination of N-Nitroso Compounds Based on the Differences in Reactivity to Denitrosating Reagents(Envionmental)

スポンサーリンク

概要

• 論文の詳細を見る

• The denitrosation of eleven N-nitroso compounds was followed by using a modification of the method of Eisenbrand and Preussmann. N-Nitroso compounds (except nitrosamides) whose precursor amines had pK_a values smaller than about 10.7 were found to be denitrosated instantaneously on addition of hydrogen bromide/acetic acid. These easily denitrosatable compounds were determined selectively with hydrogen chloride/acetic acid. The order of increasing difficulty in denitrosation of N-nitroso compounds as judged from the reactivity with the above reagents coincided well with that of pK_a values of the precursor amines.

• 公益社団法人日本薬学会の論文
• 1987-09-25

著者

• Ohta T

  Faculty Of Pharmaceutical Sciences Science University Of Tokyo

• Ohta Takafumi

  Faculty Of Pharmaceutcal Sciences Science University Of Tokyo

• Takitani Shoji

  Faculty Of Pharmaceutical Sciences Science University Of Tokyo

• KOJIMA KIMIKO

  Faculty of Pharmaceutical Sciences, Science University of Tokyo

• Kojima Kimiko

  Faculty Of Pharmaceutical Sciences Science University Of Tokyo

関連論文

• ^N-ENRICHED POLYAMINES : SYNTHESES AND APPLICATION FOR STUDIES ON POLYAMINE METABOLISM
• Content of N-Nitroso Compounds and Mutagenicity in 35 Japanese Foods after Treating with Nitrite(Food & Nutrition)
• Determination of L-Ascorbic Acid by a Flow Injection Analysis with Copper(II)-Mediated Electrochemical Detection
• Optical Resolution of Thiol Enantiomers by High-Performance Liquid Chromatography Using Precolumn Fluorescence Derivatization with ο-Phthaladehyde and α-Amino Acids
• Chiral Separation by Curdlan Gel Electrophoresis
• SUPPLEMENTAL STUDIES ON FLUOROPHORE IN REACTIONS OF EPOXIDES WITH NICOTINAMIDE AND ACETOPHENONE
• FLUORESCENCE REACTION OF COMMON EPOXIDES WITH NICOTINAMIDE AND ACETOPHENONE
• Fluorometric Determination of Phenylpyruvic Acid with 1,4-Dimethyl-3-carbamoylpyridinium Chloride(Analytical,Chemical)
• Classification and Determination of N-Nitroso Compounds Based on the Differences in Reactivity to Denitrosating Reagents(Envionmental)
• Selective extraction of β-blockers from biological fluids by column-switching high-performance liquid chromatography using an internal-surface phenylboronic acid precolumn
• Formation of Mutagens by the Reaction of Amino Acids with Nitrite in Acidic Solution

もっと見る 閉じる

スポンサーリンク