Studies on Diazepines. XXV. : Syntheses of Fully Unsaturated 1,4-Oxazepines and 1H-1,4-Diazepines Using Photochemical Valence Isomerization of Tricycloheptene Systems(Organic,Chemical)

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概要

• 論文の詳細を見る

• 3-Azatricyclo[4.1.0.0^<2.5>]hept-3-ene derivatives prepared from pyridines via five steps were found to be useful synthons for fully unsaturated monocyclic seven-membered heterocyclic rings. Photolysis of the 7-oxa derivatives 15 resulted in valence isomerization with ring opening to give the 1,4-oxazepines (19), which are the first examples of fully conjugated 1,4-oxazepines. Similarly, the 7-aza derivatives 16, upon irradiation, afforded the novel 1H-1,4-diazepines (20). The 2,7-dimethyi-1,4-oxazepine (19c) and 2,7-dimethyl-1,4-diazepine (20c) underwent thermal ring conversion, giving rise to the 1,3-oxazepine (22) and 1,3-diazepine (24), respectively.

• 公益社団法人日本薬学会の論文
• 1987-08-25

著者

• Kurita Jyoji

  School Of Pharmacy Hokkaido University

• TSUCHIYA TAKASHI

  School of Pharmacy, Hokuriku University

• Tsuchiya T

  National Inst. Hygienic Sciences Tokyo Jpn

• IWATA KUNIYOSHI

  School of Pharmacy, Hokkaido University

• Iwata Kuniyoshi

  School Of Pharmacy Hokkaido University

• Tsuchiya Takashi

  School Of Pharmacy Hokuriku University

関連論文

• Studies on Diazepines. XXVII. : Syntheses of Fully Unsaturated 1H- and 3H-1,4-Benzodiazepines form 4-Quinolyl Azides(Organic,Chemical)
• Studies on Diazepines. XXVI. : Syntheses of 6H-1,4-Diazepines and 1-Acyl-1H-1,4-diazepines from 4-Pyridyl Azides(Organic,Chemical)
• Studies on Diazepines. XXV. : Syntheses of Fully Unsaturated 1,4-Oxazepines and 1H-1,4-Diazepines Using Photochemical Valence Isomerization of Tricycloheptene Systems(Organic,Chemical)

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