ENHANCEMENT OF IA-LIKE ANTIGEN EXPRESSION BY INTERFERON-GAMMA IN POLYMORPHONUCLEAR LEUKOCYTES(Communications to the Editor)
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概要
- 論文の詳細を見る
The effects of interferons (IFNs) on la-like antigen expression in human peripheral blood polymorphonuclear leukocytes (PMNs) were examined in vitro using flow cytometry and FITC-labelled monoclonal antibody specific for the Ia-like antigen OKIa1. Recombinant human IFN-gamma markedly enhanced the expression of Ia-like antigen on PMNs and increased the number of Ia-positive PMNs. In contrast, natural human IFN-alpha and -beta had no effect on the expression when compared on the basis of antiviral activity.
- 社団法人日本薬学会の論文
- 1987-01-25
著者
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森山 雅美
Basic Research Laboratories Toray Industries Inc.
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松本 修
Basic Research Laboratories, Toray Industries Inc.
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竹井 真紀子
Basic Research Laboratories, Toray Industries Inc.
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今西 英世
Basic Research Laboratories, Toray Industries Inc.
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松本 修
Basic Research Laboratories Toray Industries Inc.
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今西 英世
Basic Research Laboratories Toray Industries Inc.
-
竹井 真紀子
Basic Research Laboratories Toray Industries Inc.
関連論文
- Augmentation of Antibody-Dependent Cellular Cytotoxicity of Polymorphonuclear Leukocytes by Interferon-Gamma : Mechanism Dependent on Enhancement of Fc Receptor Expression and Increased Release of Activated Oxygens(Pharmacological)
- ENHANCEMENT OF IA-LIKE ANTIGEN EXPRESSION BY INTERFERON-GAMMA IN POLYMORPHONUCLEAR LEUKOCYTES(Communications to the Editor)
- Effects of Recombinant Human Interferon-Gamma (Met-Gln Form) on Expression of Fc Receptor and Ia-like Antigen on Human Peripheral Monocytes and Lymphocytes: A Comparative Study with Natural Human Interferon-Alpha and -Beta(Pharmacological)
- Effect of Interferon on Activated Oxygen Production in Human Monocytes in Vitro : Direct Measurement of Phagosomal Activated Oxygens by a New Method Using Luminol-Binding Microspheres
- Characteristics of Augmentation of Cell-Mediated Cytotoxic Activities by Recombinant Human Interferon-Gamma (Met-Glu Form) : A Comparative Study with Natural Human Interferon-Alpha and -Beta