Synthesis of Isomeric, Oxathiolone Fused Chalcones, and Comparison of Their Activity toward Various Microorganisms and Human Cancer Cells Line
スポンサーリンク
概要
- 論文の詳細を見る
Isomeric oxathiolone fused chalcones were prepared by condensation of appropriate acetylbenzo[1,3]-oxathiol-2-ones with benzaldehydes under acidic conditions. The synthesized compounds were screened for cytotoxic activity using HeLa cells, as well as for antibacterial activity against Micrococcus luteus, Staphylococcus aureus, Salmonella typhimurium, Escherichia coli, Proteus vulgaris, antifungal activity against Candida albicans, and tuberculostatic activity against Mycobacterium tuberculosis H_<37>Rv and Mycobacterium kansasii strains.
- 公益社団法人日本薬学会の論文
- 2007-05-01
著者
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Konieczny Marek
Department Of Organic Chemistry Medical University Of Gdansk
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Konieczny Wojciech
Department Of Organic Chemistry Medical University Of Gdansk
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SABISZ Michal
Department of Pharmaceutical Technology and Biochemistry, Gdansk University of Technology
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SKLADANOWSKI Andrzej
Department of Pharmaceutical Technology and Biochemistry, Gdansk University of Technology
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WAKIEC Roland
Department of Pharmaceutical Technology and Biochemistry, Gdansk University of Technology
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AUGUSTYNOWICZ-KOPEC Ewa
Department of Microbiology, National Research Institute of Tuberculosis and Lung Diseases
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ZWOLSKA Zofia
Department of Microbiology, National Research Institute of Tuberculosis and Lung Diseases
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Sabisz Michal
Department Of Pharmaceutical Technology And Biochemistry Gdansk University Of Technology
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Skladanowski Andrzej
Department Of Molecular Enzymology Intercollegiate Faculty Of Biotechnology Medical University Of Gd
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Skladanowski Andrzej
Department Of Pharmaceutical Technology And Biochemistry Gdansk University Of Technology
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Augustynowicz-kopec Ewa
Department Of Microbiology National Research Institute Of Tuberculosis And Lung Diseases
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Zwolska Zofia
Department Of Microbiology National Research Institute Of Tuberculosis And Lung Diseases
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Wakiec Roland
Department Of Pharmaceutical Technology And Biochemistry Gdansk University Of Technology
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