脳下垂体摘出がストレス耐性に与える効果 : シリアンハムスターの精巣・体重発達を指標として

概要

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The present experiment was performed to clarify the effect of hypophysectomy onstress tolerance in the Syrian hamster using indicators of body weight and testes weight.Stress was produced by unpredictable deprivation of food on 30% of the days during the6-week long photoperiods. We hypothesized that hypophysectomy attenuate stress tolerance,and thus prevent the growth of body weight and testes weight compared to thesham-operated animals. The present findings clearly showed that the body weight gainwas more suppressed in the hypophysectomized animals than that in the sham operatedones. Our results also clearly indicated that the testicular weight/ 100g B.W in the hypophysectomizedanimals was more suppressed than that in the sham-operated ones and thus,the suppression ratio (SR) in the hypophysectomized animals was much higher than thatin the sham-operated ones. The working hypothesis that stress tolerance will be attenuatedby hypophysectomy was confirmed in the long photoperiods from the present findings.