菌破壊液滴下により発生したイヌの初期歯肉炎について : 第2報特にFusobacterium菌破壊液の免疫犬を使用した場合

概要

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The aim of present study was to examine the effect of immunization on the initial inflammatory changes in the marginal gingiva. Two dogs were used. After Fusobacterium sonicate was topically applied to two jaw quadrants of the dogs with clinically healthy gingivae for 8 hours, gingival strips were obtained. Furthermore, similar topical application was carried out in the remaining quadrants of the dogs which had been immunized by Fusobacterium sonicate and the gingival strips were also taken. The gingival strips were fixed in 10% formalin and embedded in paraffin. The serial buccolingual cross sections of 5μm thickness were prepared and stained with hematoxylin and eosin, Masson・Goldner and PAS・Alcian blue. The histologic sections showed that in the immunized dog, after topical application of Fusobacterium sonicate the numbers of polymorphonuclear leucocytes in the marginal gingiva tended to increase as compared with those before immunization. This fact may reflect the leucocyte chemotaxis via complement activation in a classical pathway.
特定非営利活動法人日本歯周病学会の論文
1981-12-28